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March 5 , 2001

Tetanus Vaccine Shortage Worsens


Hernán Rozemberg The Arizona Republic

A shortage of tetanus vaccine shots has worsened, leaving many hospitals and clinics across the country with only a week-to-week supply.

Though no Arizona medical center has yet run out of the tetanus vaccine, the shortage has many doctors biting their nails as they await the next small shipment.

In mid-January, Wyeth-Ayerst, one of the nation's two tetanus manufacturers, announced that it was stopping production of both child and adult versions of the vaccine.

"It caught us all by surprise," said Len Lavenda, spokesman with Aventis Pasteur, the Pennsylvania-based company now responsible for developing the vaccine for the entire country. "We never thought they were making a permanent exit from the market."

It is estimated the shortage could continue for up to 18 months. Lavenda said it will take at least until the end of the year before supply meets demand for the adult brand - more commonly known as "10-year booster shots."

Until then, orders are being "rationed," meaning, for example, that a hospital asking for 1,000 doses will get only 100 doses.

It also will take several months before the children's version, a series of five shots given between birth and age 5, is no longer on back order, said Lavenda, who pointed out that it takes nearly a year to grow the bacteria to make the vaccine.

The Centers for Disease Control and Prevention in Atlanta, the U.S. government's health monitor, doesn't see a need to panic. But "spot shortages" may be worse in parts of the country that are further down on the waiting list, spokeswoman Barbara Reynolds said.

Lavenda also sees no need to worry. If hospitals or doctors run out, all they need to do is ask for help - an emergency supply is always kept handy, he said.

Even so, Arizona health officials would like to prevent such a scenario. They're calling for temporary changes until the shortage ends.

"When you have to be putting new orders in every week and you're used to a regular three-month supply, it makes everyone nervous," said Kathy Frederickson, who runs Arizona's Immunization Program. The program is the vaccine distributor for nearly 800 public hospitals and clinics across the state.

Frederickson's office dispatched a memo to all medical centers in the state saying they may keep only up to one month's reserve of the children's version. They also must list how many shots were given the previous month and their current stock or they won't be given more.

The memo also asks that the last shot kids get before entering kindergarten be delayed until they're 5 to 6 years old - many children get this shot when they're 4.

The 10-year boosters are required to attend school, but due to the shortage, school nurses are being told to let students in even if they haven't had them.

"We're being told to use it only for students with injuries," Mesa High School nurse Marilyn Brown said.

Medical workers are nervous but aren't sounding the alarm - at least not yet.

"It's a big change in practice for us," said Marcia Dern, a Phoenix Children's Hospital nurse who serves many low-income, uninsured children that depend on free shots. "Normally, if I have a 4-year-old in the office, I don't have to think about not giving a tetanus shot."

Gary Baker, pharmacy director for the privately run Scottsdale Healthcare hospitals, has nightmares of having to turn people away.

"We haven't run bone-dry yet, but we've often been down to our last vial," he said. "It'll be a really big deal when a patient shows up and cannot be served."

According to the Centers for Disease Control, tetanus is a potentially fatal disease that stiffens the body's muscles and produces spasms, usually starting with the jaw area. The bacterium that causes tetanus usually comes from the soil and enters through a wound.

Elderly people are most vulnerable, primarily because they haven't had tetanus shots in many years. During the 1990s, a larger number of younger people became infected, mostly through the use of drug needles.

The number of cases has dramatically dropped. While as many as 600 people in the United States died of tetanus in the late 1940s, an all-time low of 33 deaths was reported in 1999.

 

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