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February 26 ,2001

Biotech Insect Has Jellyfish Gene

Associated Press

By tinkering with genes, scientists have made tomatoes that stay fresher longer, crops that are immune to weedkillers and fish that grow faster. Now, a genetically engineered insect is emerging from the lab.

The first field trial of a biotech insect — a pink bollworm moth that contains a jellyfish gene — is planned for this summer. The gene gives the moth larvae a fluorescence.

If the experiment involving a major pest for cotton growers goes as planned, scientists are ready with their next step: testing a biotech version, called the "Terminator" by farmers, that is sterile, but sexually active; it is designed to mate with wild relatives and eliminate their offspring.

Some 3,600 moths with the jellyfish genes are to be set free under screened cages in a government-owned cotton field near Phoenix. The next step would be to add genes that make the moths sterile.

"We're being very, very careful about what we're doing," said Robert Staten, an Agriculture Department scientist who will run the field trial.

The experiment is being conducted and regulated by department's Animal and Plant Health Inspection Service because of its authority for controlling plant pests. Staten expects the agency to grant approval this spring for the release.

"We're going to take as conservative an approach as we can and still move forward," he said.

Some biotech critics are alarmed while some scientists who support the technology say the government is not prepared to properly regulate biotech insects.

Under development, for example, are disease-preventing mosquitoes that could deliver vaccines to the people they bite or carry their own antibiotics.

"When you're talking about insects you're talking about extremely promiscuous organisms that will mutate and breed quite uncontrollably," said Charles Margulis, an anti-biotech activist with the environmental group Greenpeace.

He said there is no guarantee that an insect designed to be sterile will turn out that way.

The pink bollworm moth infects about 500,000 acres of cotton in the Southwest. Farmers have three options to control them: spraying a lot of insecticide; planting an expensive variety of genetically engineered cotton that makes its own insecticide; or by releasing moths sterilized by irradiation.

Irradiated moths are less effective in areas with heavy infestation because the treatment damages the insects so much that they are slow to mate. The genetically engineered moth is designed to have the same sexual prowess as its wild cousins.

"He'd be fully sexually aggressive and go out and meet and breed. He'd be the first guy in the bars at night," said John Benson, a farmer in California's Imperial Valley and a member of the California Cotton Pest Control Board, which has funded the research through producer fees.

"We see this as the one sure way to get eradication," he said.


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