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September 14 , 2000

Shot Plus Vaccine Man Prevent Polio

The Associated Press - A new study has found that giving a booster shot in addition to the oral polio vaccine is the best way to ensure that babies in Third World countries are protected from the virus.

In industrialized countries, three doses of oral vaccine are 95 percent effective in protecting children. But the rate in developing countries is as low as 65 percent, perhaps because youngsters there are resistant to the vaccine or the vaccine is not properly refrigerated.

In a study, researchers gave either booster shots or extra doses of an oral vaccine to 785 9-month-old babies in Oman who had already gotten five doses of oral vaccine. Only the booster shots proved effective.

The booster shots kept antibody levels high for at least six months, Dr. Roland W. Sutter of the Centers for Disease Control and Prevention reported in Thursday's New England Journal of Medicine.

The polio vaccine works by spurring the immune system to make protective antibodies. Polio shots contain dead polio virus; the oral vaccine contains a live but weakened virus.

Although it has been nine years since the last case of polio in the Western Hemisphere, the virus is still found in 30 countries in South Asia and sub-Saharan Africa.

 


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